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Enchondroma

  • Most common benign cystic lesion of the phalanges
  • Calcified chondroid matrix except when in the phalanges (possible in phalanges but rare)
  • Lack of calcified chondroid matrix anywhere else should take enchondroma off ddx
  • Very difficult to differentiate from chondrosarcoma on imaging as well as on biopsy
    • Therefore not routinely biopsied and more often followed with serial imaging
    • Any chondroid lesion can look malignant when biopsied
  • Enchondroma shouldn't have periostitis
  • Multiple enchondromas termed [[Ollier disease]] (less rare)
  • Multiple enchondromas associated with soft tissue hemangiomas is known as [[Mafucci syndrome]] (rare)
Discriminators
  • Must have calcification (except phalanges)
  • No periostitis